Topiramate Side Effects

Topiramate is a dangerous drug

Topiramate is a dangerous anti-seizure drug which may cause unwanted life-threatening side effects and birth defects. If you have been diagnosed with topiramate side effects or your baby was born with a birth defect, you may win compensation against its manufacturer and/or your health care professional. You may want to contact a personal injury law firm to help you file a lawsuit.


The drug belongs to a class of drugs called anticonvulsants. Topiramate works by lowering abnormal excitement in the brain. It is prescribed by health care professionals for the treatment of seizures in those diagnosed with:

  • Epilepsy
  • Lennox-Gastaut syndrome
  • Migraine headaches

Topiramate side effects

Topiramate is prescribed to help treat certain types of seizures. Topiramate however does not cure epilepsy. It is sold in the market as Topamax, Topiragen, etc. Topiramate can trigger the following side effects, which may require seeing a doctor at once:

  • Unusual weakness or tiredness
  • Trouble paying attention or concentrating
  • Language or speech problems
  • Nervousness
  • Menstrual pain
  • Menstrual changes
  • Memory problems
  • Increased eye pressure
  • General slowing down of physical and mental activity
  • Eye redness
  • Drowsiness
  • Dizziness
  • Uncontrollable and continuous rolling eye movements
  • Confusion
  • Unsteadiness or clumsiness
  • Tingling, prickling or burning sensations
  • Visions problems like blurred vision, rapidly decreasing vision, eye pain and double vision

The use of topiramate may also trigger the following less common side effects:

  • Weight loss
  • Bleeding, irritated or red gums
  • Depression, irritability, apathy, agitation, aggression and mental or mood changes
  • Loss of appetite
  • Lessening of perception or sensations
  • Sore throat, chills or fever
  • Stomach or abdominal pain

The following side effects are rare; nevertheless topiramate is capable of causing:

  • Trouble breathing
  • Swelling
  • Skin rash
  • Buzzing or ringing in the ears
  • Irritated or red eyes
  • Pale skin
  • Nosebleeds
  • Side or lower back pain
  • Loss of bladder control
  • Itching
  • Hearing loss
  • Frequent urination
  • Eye pain
  • Painful or difficult urination
  • Decrease in sexual drive
  • Blood in the urinal pain

Symptoms of a Topiramate overdose

Those suffering from the drug's overdose may have the following symptoms and must seek immediate help:

  • Unusual sweating
  • Stomach cramps
  • Severe sleepiness
  • Restlessness
  • Deep, rapid breathing
  • Nausea
  • Muscle tremors
  • Sluggishness, weakness, tiredness, dullness and drowsiness
  • Lightheadedness, faintness or dizziness especially when standing up suddenly from sitting or lying position
  • Decreased responsiveness or awareness

Topiramate and birth defects

The use of the drug by pregnant women increases the likelihood of giving birth to a child with a birth defect. A study by the North American Antiepileptic Drug Pregnancy Registry established that 3.8 percent of pregnant women using the drug gave birth to children with serious birth defects as compared to 1.3 percent of those who did not use the drug. Topiramate babies may be born with lower birth weight or cleft lip and palate disorder. Some of the symptoms of the disorder are:

  • Small notch in the lip
  • Complete split in the lip extending to the base of the nose
  • Poorly aligned teeth
  • Change in nose shape

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